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JNJ-67856633 leads to potent in vivo pharmacodynamic shutdown in CD79b- as well as CARD11-mutant ABC-DLBCL models as measured by serum IL10 or uncleaved BCL10 levels in tumors
with a maximal plasma concentration of 3 μM and bioavailability of 48%
InChi: InChI=1S/C13H15NO2/c1-3-13(15)14-7-6-10(2)11(9-14)12-5-4-8-16-12/h3-5
Smiles: CC1=CC(NC)=NC(NC2=CC(=C(C=C2)OC)N2C=C(CNC)C=N2)=N1
Formula: C141H218N40O48
Azido-PEG1-azide 7409 JNJ-67856633 leads to potent inAzido PEG1 azide is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 24345 74 2 Molecular Weight: 156. 15 Formula: C4H8N6O Chemical Name: 1 azido 2 (2 azidoethoxy)ethane Smiles: [N ]=[N+]=NCCOCCN=[N+]=[N ] InChiKey: NQEPBRYUGPSVPU UHFFFAOYSA N InChi: InChI=1S C4H8N6O c5 9 7 1 3 11 4 2 8 10 6 h1 4H2 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis)